February 28, 2015
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Targeting Dual Points of Entry

Posted on February 18, 2015 by in LifeGuide, Treatment Horizons

LifeGuide [Treatment Horizons] Two Birds, One Stone Researchers make advances with agents that can target dual points of entry by Mariel Selbovitz, MPH Drug discovery and early to mid-stage drug development for HIV primarily takes place at academic institutions and small biotechnology companies. At the Frontiers in Developing Antiretroviral Therapy Conference (HIV DART 2014), which [...]

Responding to TB

Posted on January 23, 2015 by in LifeGuide, Treatment Horizons

LifeGuide [Treatment Horizons] Rapid Response Why advances in point-of-care TB diagnostics determine the future of the AIDS crisis by Mariel Selbovitz, MPH TB—one of the greatest killers and what appears to be the most persistent of our public health threats—still lacks effective widespread utility of rapid point-of-care diagnostics to quickly and accurately diagnosis TB infection. [...]

Developing Doravirine

Posted on December 23, 2014 by in LifeGuide, Treatment Horizons

LifeGuide [Treatment Horizons] Running Into Options An NNRTI candidate seeks to keep on track to expand therapies by Chael Needle In this next-generation era of anti-HIV meds, research and development has turned to candidates with alternative functions, like reducing HIV reservoirs; candidates with better side effect profiles; candidates with simplified dosing—in short, better therapeutic options. [...]

The Road Ahead

Posted on December 11, 2014 by in LifeGuide, Treatment Horizons

LifeGuide Treatment Horizons The Road Ahead New candidates hold promise for ARV therapy & therapeutic vaccines by Mariel Selbovitz, MPH The 54th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2014) took place on September 5–9 in Washington, D.C. ICAAC has long been a premier conference for HIV research with investigators from around the globe [...]

Heart Break in Melbourne

Posted on November 5, 2014 by in LifeGuide, Treatment Horizons

LifeGuide [Treatment Horizons] Heart Break in Melbourne Cardiovascular disease studies focus on assessment, management & treatment by Jeannie Wraight Cardiovascular disease (CVD) has become a leading cause of illness and death in people living with HIV. CVD now accounts for twenty percent of deaths in HIV-positive people. Researchers and clinicians continue to piece together a [...]

New Nukes, Old Nukes

Posted on October 6, 2014 by in LifeGuide, Treatment Horizons

[Treatment Horizons] Nuclear Waste How to get overwhelmed by the data on new nukes, old nukes & lots of different classes of ART at AIDS 2014 by Mariel Selbovitz, MPH, and David Miller The summer of AIDS 2014 this July in Melbourne saw the community move beyond the wave of incidental, failed attempts at a [...]

Barriers to Treatment Use

Posted on August 27, 2014 by in LifeGuide, Treatment Horizons

LifeGuide [Treatment Horizons] Opening Doors A new survey uncovers barriers to treatment by Chael Needle There’s an old chestnut that goes something like this: People won’t make a change until they want to make a change. In our present context of low treatment rates, change—linking to and staying in care for those aware of their [...]

HIV Therapeutic Vaccine Advances

Posted on July 24, 2014 by in LifeGuide, Treatment Horizons

Treatment Horizons Another Kind of Morning HIV therapeutic vaccines try to come of age by Mariel Selbovitz, MPJ, and David Miller Despite over three decades of research on therapeutic vaccines for the treatment of HIV, clinical advances have been slow in coming for this important class of drug. While there are a plethora of therapeutic [...]

New Treatment Guidelines

Posted on June 23, 2014 by in LifeGuide, Treatment Horizons

LifeGuide [Treatment Horizons] New Guidelines Revised treatment strategies address cost, monitoring & choosing a regimen by Chael Needle Revised guidelines for HIV treatment approaches will help you and your physician figure out how to fine-tune your regimen, now or when you might need to do so in the future. Reported in Guidelines for the Use [...]

Editing Genes for a Cure

Posted on April 11, 2014 by in LifeGuide, Treatment Horizons

Close to the Edit A functional cure candidate modifies genes to create HIV-resistant cells by Chael Needle Gary Blick, MD, AAHIVS, Medical & Research Director of CIRCLE CARE Center and Chief Medical Officer of World Health Clinicians, doesn’t throw the word “cure” around lightly. As an HIV physician for over thirty years, he remembers when [...]